Description

[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-pyrimidine core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.

Basic Information

Product Name	[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol
CAS No.	1353958-70-9
Molecular Formula	C12H19N3O2S
Molecular Weight	269.36 g/mol
Synonyms	4-Piperidinemethanol, 1-[6-methoxy-2-(methylthio)-4-pyrimidinyl]-; 1-(6-Methoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-ylmethanol; (1-(6-Methoxy-2-(methylsulfanyl)pyrimidin-4-yl)piperidin-4-yl)methanol; 4-((6-Methoxy-2-(methylthio)pyrimidin-4-yl)amino)piperidine-4-methanol (tautomer); CAS 1353958-70-9
EINECS	Contact for details

Quality Control

Our [1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.