Description

[1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry Development: Serves as a critical intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	[1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353956-57-6
Molecular Formula	C16H26N4O3
Molecular Weight	322.41 g/mol
Synonyms	tert-Butyl N-[1-(6-ethoxypyrimidin-4-yl)piperidin-4-yl]carbamate; 1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl-Carbamic Acid tert-Butyl Ester; BOC-4-AP-6-ethoxypyrimidine; 4-[[(tert-Butoxy)carbonyl]amino]-1-(6-ethoxypyrimidin-4-yl)piperidine; UNII-8V1K8W8Q1F (component); 1353956-57-6; 1-(6-Ethoxy-pyrimidin-4-yl)-piperidin-4-yl-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our [1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.