Description

4,6-Bis-(Piperidin-4-Yloxy)-Pyrimidine Dihydrochloride is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore building block and versatile intermediate for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D organizations, contract research and manufacturing (CRO/CMO) companies, and academic research institutions engaged in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological targets and mechanisms.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and organic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities.

Basic Information

Product Name	4,6-Bis-(Piperidin-4-Yloxy)-Pyrimidine Dihydrochloride
CAS No.	1353956-54-3
Molecular Formula	C14H24Cl2N4O2
Molecular Weight	351.27 g/mol
Synonyms	4,6-Bis(4-piperidinyloxy)pyrimidine dihydrochloride; 4,6-Di(piperidin-4-yloxy)pyrimidine dihydrochloride; 4,6-Bis(piperidin-4-yloxy)pyrimidine hydrochloride (1:2); Pyrimidine, 4,6-bis(4-piperidinyloxy)-, dihydrochloride; 4,6-Bis(4-piperidyloxy)pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4,6-Bis-(Piperidin-4-Yloxy)-Pyrimidine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.