Description

n-Cyclopropyl-N'-Piperidin-2-Ylmethyl-Pyrimidine-4,6-Diamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific diaminopyrimidine core structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other enzyme-targeting molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during early-stage drug discovery.
• Biochemical Tool Compound: May be employed in vitro to study biological pathways and validate novel therapeutic targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	n-Cyclopropyl-N'-Piperidin-2-Ylmethyl-Pyrimidine-4,6-Diamine Hydrochloride
CAS No.	1353956-39-4
Molecular Formula	C14H24N6 • HCl
Molecular Weight	304.84 g/mol (Free base: 268.38 g/mol)
Synonyms	4,6-Pyrimidinediamine, N-cyclopropyl-N'-(2-piperidinylmethyl)-, monohydrochloride; 4,6-Diamino-N-cyclopropyl-N'-(piperidin-2-ylmethyl)pyrimidine hydrochloride; UNII-9P3K6T86J2; 9P3K6T86J2; n-Cyclopropyl-N'-(2-piperidinylmethyl)-4,6-pyrimidinediamine hydrochloride; 1353956-39-4; 4,6-Diamino-N-cyclopropyl-N'-[(2-piperidinyl)methyl]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-N'-Piperidin-2-Ylmethyl-Pyrimidine-4,6-Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.