Description

1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Serves as a precursor for creating more complex, functionalized piperidine and pyrimidine derivatives.
• API Development: Integral component in the development and scale-up processes for new active pharmaceutical ingredients.
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylamine Hydrochloride
CAS No.	1353955-90-4
Molecular Formula	C13H22N4OS • HCl
Molecular Weight	330.86 g/mol (Free base: 294.41 g/mol)
Synonyms	4-Amino-1-(6-ethoxy-2-(methylthio)pyrimidin-4-yl)piperidine hydrochloride; 1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-amine hydrochloride; 4-Piperidinamine, 1-[6-ethoxy-2-(methylthio)-4-pyrimidinyl]-, hydrochloride; 1-(6-Ethoxy-2-methylsulfanylpyrimidin-4-yl)piperidin-4-amine HCl
EINECS	Contact for details

Quality Control

Our 1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.