Description

3-(6-Ethoxy-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core linked to an ethoxy-pyrimidine moiety. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing therapeutics for central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the synthetic route for complex molecules, leveraging its piperidine and pyrimidine functional groups.
• Fine Chemical Manufacturing: Serves as a specialized building block for the production of high-value, low-volume chemicals used in life sciences.
• Contract Research Organization (CRO) & Contract Development and Manufacturing Organization (CDMO) Services: Supplied to organizations providing outsourced R&D and manufacturing for the pharmaceutical industry.

Basic Information

Product Name	3-(6-Ethoxy-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353955-56-2
Molecular Formula	C16H25N3O4
Molecular Weight	323.39 g/mol
Synonyms	1-Boc-3-((6-ethoxy-4-pyrimidinyl)oxy)piperidine; tert-Butyl 3-((6-ethoxy-4-pyrimidinyl)oxy)-1-piperidinecarboxylate; 3-[(6-Ethoxy-4-pyrimidinyl)oxy]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-[(6-ethoxy-4-pyrimidinyl)oxy]-1-piperidinecarboxylate; 3-(6-Ethoxy-pyrimidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-(6-ethoxy-pyrimidin-4-yloxy)-piperidine; BOC-3-(6-Ethoxy-4-pyrimidinyloxy)piperidine
EINECS	Contact for details

Quality Control

Our 3-(6-Ethoxy-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.