Description

4-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile piperidine-pyrimidine scaffold for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	4-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353955-46-0
Molecular Formula	C16H26N4O3
Molecular Weight	322.41 g/mol
Synonyms	tert-Butyl 4-[(6-methoxypyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(6-methoxypyrimidin-4-yl)amino]piperidine; 4-(6-Methoxy-4-pyrimidinyl)amino-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 4-[(6-Methoxypyrimidin-4-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-methoxypyrimidin-4-yl)amino]piperidine; Boc-4-(6-Methoxy-pyrimidin-4-ylamino)-piperidine
EINECS	Contact for details

Quality Control

Our 4-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.