Description

3-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on drug discovery programs, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel small-molecule drug candidates.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Integral in the production route for complex Active Pharmaceutical Ingredients (APIs), particularly kinase inhibitors.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353955-36-8
Molecular Formula	C15H24N4O3
Molecular Weight	308.38 g/mol
Synonyms	tert-Butyl 3-[(6-methoxypyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-Boc-3-[(6-methoxypyrimidin-4-yl)amino]piperidine; 3-(6-Methoxy-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[(6-methoxypyrimidin-4-yl)amino]piperidine; 3-((6-Methoxypyrimidin-4-yl)amino)piperidine-1-carboxylic acid tert-butyl ester; BOC-3-(6-Methoxy-pyrimidin-4-ylamino)-piperidine; 1353955-36-8
EINECS	Contact for details

Quality Control

Our 3-(6-Methoxy-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.