Description

1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-carboxylic acid core linked to a methoxypyrimidine moiety. This compound matters as a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to develop new drug candidates and high-value fine chemicals. Its defined structure enables efficient downstream functionalization and supports the creation of compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators that utilize pyrimidine-based chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fine chemicals for client projects.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid
CAS No.	1353955-34-6
Molecular Formula	C11H15N3O3
Molecular Weight	237.26 g/mol
Synonyms	1-(6-Methoxypyrimidin-4-yl)piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-(6-methoxy-4-pyrimidinyl)-; Piperidine-3-carboxylic acid, 1-(6-methoxy-pyrimidin-4-yl)-; 1-(6-Methoxy-4-pyrimidinyl)-3-piperidinecarboxylic acid; 1-(6-Methoxypyrimidin-4-yl)nipecotic acid; 1353955-34-6; 1-(6-Methoxy-pyrimidin-4-yl)-piperidin-3-carbonsäure (German)
EINECS	Contact for details

Quality Control

Our 1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our commitment to quality supports your research integrity and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.