Description

3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, antiviral, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for clinical trials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Biochemical Research: Can be utilized as a tool compound for probing biological pathways and target validation.

Basic Information

Product Name	3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353944-47-4
Molecular Formula	C17H26N6O2
Molecular Weight	346.43 g/mol
Synonyms	tert-Butyl 3-[(6-(cyclopropylamino)pyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-Boc-3-[(6-(cyclopropylamino)pyrimidin-4-yl)amino]piperidine; 1-(tert-Butoxycarbonyl)-3-[(6-(cyclopropylamino)pyrimidin-4-yl)amino]piperidine; 3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester; BOC-protected Cyclopropylamino Pyrimidine Piperidine Intermediate; CAS 1353944-47-4
EINECS	Contact for details

Quality Control

Our 3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.