Description

2-Bromo-5-Cyclopropylpyrimidine is a high-purity halogenated pyrimidine building block of significant importance in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for use as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand Synthesis: Used to prepare novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-5-Cyclopropylpyrimidine
CAS No.	1353855-47-6
Molecular Formula	C7H7BrN2
Molecular Weight	199.05 g/mol
Synonyms	5-Cyclopropyl-2-bromopyrimidine; 2-Bromo-5-cyclopropyl-pyrimidine; Pyrimidine, 2-bromo-5-cyclopropyl-; Bromo-cyclopropylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Cyclopropylpyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.