Description

2,4-Dichloro-6-(Cyclobutyl)Pyrimidine is a high-value, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the cyclobutyl-pyrimidine scaffold into novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold for exploring structure-activity relationships (SAR) in medicinal chemistry programs.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis or as a core structure in functional materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	2,4-Dichloro-6-(Cyclobutyl)Pyrimidine
CAS No.	1353853-74-3
Molecular Formula	C8H8Cl2N2
Molecular Weight	203.07 g/mol
Synonyms	6-Cyclobutyl-2,4-dichloropyrimidine; 2,4-Dichloro-6-cyclobutylpyrimidine; 2,4-Dichloro-6-cyclobutyl-pyrimidine; Pyrimidine, 2,4-dichloro-6-cyclobutyl-; (Cyclobutyl)dichloropyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6-(Cyclobutyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.