Description

3-Fluoro-5-(Trifluoromethoxy)Benzylamine is a high-value fluorinated aromatic amine building block. This compound is critical for introducing specific fluorine-containing motifs into target molecules, which can dramatically alter their physicochemical and biological properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy and fluorine groups can enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Incorporated into polymers and liquid crystals to modify thermal stability, solubility, and electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and diagnostic applications.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethoxy)Benzylamine
CAS No.	1353000-19-7
Molecular Formula	C8H7F4NO
Molecular Weight	209.14 g/mol
Synonyms	(3-Fluoro-5-(trifluoromethoxy)phenyl)methanamine; 1-(3-Fluoro-5-(trifluoromethoxy)phenyl)methanamine; 3-Fluoro-5-(trifluoromethoxy)benzenemethanamine; α-Amino-3-fluoro-5-(trifluoromethoxy)toluene; 3-Fluoro-5-trifluoromethoxybenzylamine; 3-Fluoro-5-(trifluoromethoxy)benzyl amine; 3-Fluoro-5-(trifluoromethoxy)phenylmethylamine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethoxy)Benzylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage at 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.