Description

3-Ethynyl-3-Fluoro-Oxetane is a high-value, multi-functional fluorinated oxetane monomer. This compound matters as a critical building block for advanced materials, enabling the precise introduction of fluorine and alkyne functional groups into polymer backbones. It is primarily needed by R&D chemists and material scientists in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel products with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing fluorine and the reactive ethynyl handle into drug candidates, potentially improving metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides where the fluorinated oxetane moiety can enhance activity and environmental profile.
• Advanced Polymer Monomer: A crucial component for synthesizing specialty polymers, including fluorinated polyethers and polyoxetanes, for high-performance coatings, elastomers, and membranes.
• Click Chemistry Substrate: The ethynyl group makes it an ideal participant in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and material surface functionalization.
• Liquid Crystal & OLED Materials: Employed in the development of fluorinated components for electronic display and lighting technologies to modify dielectric constant and stability.
• Energetic Materials Binder: Investigated for use in binders for propellants and explosives, where fluorinated polymers can offer desirable combustion and stability characteristics.

Basic Information

Product Name	3-Ethynyl-3-Fluoro-Oxetane
CAS No.	1352492-39-7
Molecular Formula	C5H5FO
Molecular Weight	100.09 g/mol
Synonyms	3-Fluoro-3-ethynyloxetane; 3-Ethynyl-3-fluorooxetane; 3-Fluoro-3-(ethynyl)oxetane; Oxetane, 3-ethynyl-3-fluoro-; 3-Fluorooxetane-3-carbaldehyde, ethynyl-; 3-Fluoro-3-ethynyl-1-oxacyclobutane
EINECS	Contact for details

Quality Control

Every batch of 3-Ethynyl-3-Fluoro-Oxetane is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, consider maintaining at 2-8°C under an inert atmosphere to preserve stability and prevent polymerization or degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.