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(5-Bromo-2-Fluoro-Phenyl)-Dimethyl-Amine CAS NO 1352214-46-0


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CAS No.:1352214-46-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(5-Bromo-2-Fluoro-Phenyl)-Dimethyl-Amine is a high-purity, halogenated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
  • Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
  • Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
  • Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
  • Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name (5-Bromo-2-Fluoro-Phenyl)-Dimethyl-Amine
CAS No. 1352214-46-0
Molecular Formula C8H9BrFN
Molecular Weight 218.07 g/mol
Synonyms N,N-Dimethyl-5-bromo-2-fluoroaniline; 5-Bromo-2-fluoro-N,N-dimethylaniline; 2-Fluoro-5-bromo-N,N-dimethylaniline; 1-Bromo-4-fluoro-5-(dimethylamino)benzene; (5-Bromo-2-fluorophenyl)dimethylamine; N,N-Dimethyl-(5-bromo-2-fluoro)aniline; 5-Bromo-2-fluoro-N,N-dimethylbenzenamine
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Quality Control

Our (5-Bromo-2-Fluoro-Phenyl)-Dimethyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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