Description

2-(5-Amino-3-tert-Butyl-1H-Pyrazol-1-Yl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[D]Pyrimidin-4-One CAS NO 1350989-10-4 is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrazole-cyclopentapyrimidinone core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other enzyme modulators.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its heterocyclic bioactivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-(5-Amino-3-tert-Butyl-1H-Pyrazol-1-Yl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[D]Pyrimidin-4-One
CAS No.	1350989-10-4
Molecular Formula	C14H19N5O
Molecular Weight	273.34 g/mol
Synonyms	2-(5-Amino-3-tert-butyl-1H-pyrazol-1-yl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one; 2-(5-Amino-3-tert-butylpyrazol-1-yl)-4,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one; 4H-Cyclopenta[d]pyrimidin-4-one, 2-(5-amino-3-(1,1-dimethylethyl)-1H-pyrazol-1-yl)-3,5,6,7-tetrahydro-; 1350989-10-4; tert-Butyl Pyrazolyl Cyclopentapyrimidinone Derivative; Amino-tert-butyl-pyrazole-cyclopentapyrimidinone
EINECS	Contact for details

Quality Control

Our production of 2-(5-Amino-3-tert-Butyl-1H-Pyrazol-1-Yl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[D]Pyrimidin-4-One adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.