Description

2-Mehtyl-6-[Bis(tert-Butoxycarbonyl)Amino]-4-Chloropyrimidine is a high-purity, protected amino pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and the development of novel drug candidates due to its reactive chloropyrimidine and protected amine functionalities.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Serves as a precursor for labeled compounds and molecular probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.
• Academic & Industrial R&D: Fundamental reagent in academic laboratories and corporate R&D departments for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Mehtyl-6-[Bis(tert-Butoxycarbonyl)Amino]-4-Chloropyrimidine
CAS No.	1350918-95-4
Molecular Formula	C15H22ClN3O4
Molecular Weight	343.81 g/mol
Synonyms	4-Chloro-2-methyl-6-[bis(tert-butoxycarbonyl)amino]pyrimidine; 2-Methyl-6-[bis(tert-butoxycarbonyl)amino]-4-chloropyrimidine; 6-[Bis(tert-butoxycarbonyl)amino]-4-chloro-2-methylpyrimidine; 4-Chloro-2-methyl-6-[(bis(tert-butoxycarbonyl)amino)]pyrimidine; 2-Methyl-4-chloro-6-[N,N-bis(tert-butoxycarbonyl)amino]pyrimidine; Boc-Protected 6-Amino-4-chloro-2-methylpyrimidine; 4-Chloro-2-methylpyrimidin-6-yl bis(tert-butyl) dicarbonate amine
EINECS	Contact for details

Quality Control

Our 2-Mehtyl-6-[Bis(tert-Butoxycarbonyl)Amino]-4-Chloropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.