Description

2,4-Dichloro-6-Methyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine CAS NO 1350738-72-5 is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, small-molecule drug candidates, particularly in oncology and other therapeutic areas. This compound is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of targeted kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate for the pilot-scale and commercial-scale synthesis of active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and the development of new synthetic methodologies.
• Biochemical Tool Compound: Potential use in the development of biochemical probes for studying specific enzymatic pathways and disease mechanisms.

Basic Information

Item	Detail
Product Name	2,4-Dichloro-6-Methyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine
CAS No.	1350738-72-5
Molecular Formula	C9H9Cl2N3
Molecular Weight	230.09 g/mol
Synonyms	2,4-Dichloro-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 6-Methyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 5,6,7,8-Tetrahydro-6-methyl-2,4-dichloropyrido[4,3-d]pyrimidine; 2,4-Dichloro-6-methyl-5,8-dihydropyrido[4,3-d]pyrimidine; Tetrahydropyridopyrimidine derivative; THPP derivative; CAS 1350738-72-5
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6-Methyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.