Description

2-[5-Fluoro-1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Pyrimidine-4,5,6-Triamine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Biochemical Research: Used as a reference standard and a core scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct fused heterocyclic systems with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	2-[5-Fluoro-1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Pyrimidine-4,5,6-Triamine
CAS No.	1350653-30-3
Molecular Formula	C17H14F2N8
Molecular Weight	368.35 g/mol
Synonyms	2-[5-Fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine; 1350653-30-3; 2-(5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine; Pyrimidine-4,5,6-triamine, 2-[5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-; 1H-Pyrazolo[3,4-b]pyridine, pyrimidine derivative
EINECS	Contact for details

Quality Control

Our production of 2-[5-Fluoro-1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Pyrimidine-4,5,6-Triamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with material that meets rigorous in-house specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.