Description

4-Bromo-2-Chloro-3-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antimicrobial agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex, halogenated dyes and pigments that require high lightfastness and color stability.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many advanced chemicals.

Basic Information

Product Name	4-Bromo-2-Chloro-3-Fluoroaniline
CAS No.	1349719-24-9
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	3-Fluoro-4-bromo-2-chloroaniline; 2-Chloro-3-fluoro-4-bromoaniline; 4-Bromo-2-chloro-3-fluorobenzenamine; Benzenamine, 4-bromo-2-chloro-3-fluoro-; 1-Amino-4-bromo-2-chloro-3-fluorobenzene; 2-Chloro-4-bromo-3-fluoroaniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-3-Fluoroaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.