Description

n-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific molecular architecture is essential. It is needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry, process R&D, and the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Process Chemistry Development: Serves as a standardized intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in biological systems.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	n-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1349718-97-3
Molecular Formula	C14H22Cl2FN2
Molecular Weight	307.24 g/mol
Synonyms	4-[(4-Fluoro-2-methylphenyl)methyl]-4-piperidinamine dihydrochloride; 1-[(4-Fluoro-2-methylphenyl)methyl]piperidin-4-amine dihydrochloride; 4-Amino-1-[(4-fluoro-2-methylbenzyl)]piperidine dihydrochloride; 4-Fluoro-2-methylbenzylpiperidin-4-amine dihydrochloride; N-[(4-Fluoro-2-methylphenyl)methyl]-4-piperidinamine dihydrochloride; 4-(4-Fluoro-2-methylbenzyl)piperidin-4-amine dihydrochloride; (4-Fluoro-2-methylbenzyl)(4-aminopiperidin-1-yl)methanone dihydrochloride (tautomeric form).
EINECS	Contact for details

Quality Control

Our n-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.