Description

2-(Oxetan-3-Yloxy)Pyrimidin-5-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique oxetane-pyrimidine hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and research institutions engaged in the discovery of new therapeutic agents, particularly in oncology and antiviral fields.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and pharmacokinetic properties of lead compounds.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	2-(Oxetan-3-Yloxy)Pyrimidin-5-Amine
CAS No.	1349709-06-3
Molecular Formula	C7H9N3O2
Molecular Weight	167.16 g/mol
Synonyms	5-Amino-2-(oxetan-3-yloxy)pyrimidine; 2-(3-Oxetanyloxy)-5-pyrimidinamine; 5-Pyrimidinamine, 2-(3-oxetanyloxy)-; Pyrimidin-5-amine, 2-(oxetan-3-yloxy)-; Oxetane-3-yloxy-pyrimidin-5-amine; 1349709-06-3; 2-(Oxetan-3-yloxy)pyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 2-(Oxetan-3-Yloxy)Pyrimidin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.