Description

Par-2 (1-6) Amide (Human) (Scrambled) is a synthetic peptide amide derivative, specifically a scrambled sequence variant of a human protease-activated receptor 2 (PAR-2) fragment. This compound is of significant value as a critical research tool and control substance in biochemical and pharmacological studies. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for investigating PAR-2 signaling pathways, validating assays, and developing therapeutic interventions.

Application

• Biochemical Research: Used as a control peptide in studies of protease-activated receptor 2 (PAR-2) function, receptor-ligand interactions, and signal transduction mechanisms.
• Pharmacological Studies: Serves as a scrambled sequence control in experiments to validate the specificity of biological responses elicited by active PAR-2 agonist or antagonist peptides.
• Assay Development & Validation: Critical for establishing baseline signals and minimizing false positives in high-throughput screening (HTS) assays and ELISA kits targeting PAR-2 activity.
• Neuroscience & Inflammation Research: Employed in models studying the role of PAR-2 in neuroinflammation, pain perception, and immune cell activation, where a non-active control is essential.
• Drug Discovery: Acts as a reference standard and negative control in the discovery and optimization of novel PAR-2-targeting therapeutics.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes conducting basic science on G-protein coupled receptors (GPCRs) and peptide biology.

Basic Information

Product Name	Par-2 (1-6) Amide (Human) (Scrambled)
CAS No.	1348395-60-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Scrambled PAR-2 (1-6) Amide; PAR-2 (1-6) Scrambled Peptide Amide; Human PAR-2 Scrambled Sequence Amide; Protease-Activated Receptor 2 (1-6) Scrambled Amide; PAR2 Scrambled Control Peptide; F2RL1 (1-6) Scrambled Amide; Inactive PAR-2 Peptide Control
EINECS	Contact for details

Quality Control

Our Par-2 (1-6) Amide (Human) (Scrambled) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Single Impurity (HPLC)	≤1.0%
Water Content (KF)	≤5.0%
Peptide Content	≥80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.