Description

1-(5-Bromopyrimidin-2-Yl)Propan-1-One is a high-purity brominated pyrimidine derivative, a crucial building block in modern synthetic organic chemistry. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), advanced materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrimidine core imparts specific biological activity.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, ligands for catalysis, and other functionalized heterocyclic compounds.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-Yl)Propan-1-One
CAS No.	1346808-91-0
Molecular Formula	C7H7BrN2O
Molecular Weight	215.05 g/mol
Synonyms	1-(5-Bromopyrimidin-2-yl)propan-1-one; 5-Bromo-2-propionylpyrimidine; 2-Propanoyl-5-bromopyrimidine; 1-(5-Bromo-2-pyrimidinyl)-1-propanone; Propan-1-one, 1-(5-bromopyrimidin-2-yl)-; 5-Bromo-2-propionyl pyrimidine; 1346808-91-0
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-Yl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be tailored to meet specific customer requirements, including research-grade and cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.