Description

5-Bromo-4-cyclopropylpyrimidine is a high-purity halogenated pyrimidine derivative, a crucial building block in modern organic synthesis. Its value lies in its versatile reactivity, particularly in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science Research: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of molecular probes and compound libraries for drug discovery and target identification.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial and research applications.

Basic Information

Item	Detail
Product Name	5-Bromo-4-cyclopropylpyrimidine
CAS No.	1346697-39-9
Molecular Formula	C7H7BrN2
Molecular Weight	199.05 g/mol
Synonyms	4-Cyclopropyl-5-bromopyrimidine; 5-Bromo-4-cyclopropyl-pyrimidine; 5-Bromo-4-cyclopropylpyrimidine; 4-Cyclopropyl-5-bromo-pyrimidine; Pyrimidine, 5-bromo-4-cyclopropyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-cyclopropylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.