Description

2-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-1,3-Dioxolane is a high-value fluorinated and sulfonated aromatic dioxolane derivative, serving as a critical synthetic intermediate. Its unique structure, featuring both a fluorine atom and a methylsulfonyl group, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and sulfone groups can enhance biological activity and environmental stability.
• Material Science: Building block for advanced polymers and liquid crystals, where its aromatic and polar functional groups contribute to thermal stability and specific optical properties.
• Organic Synthesis: Versatile reagent for constructing complex heterocyclic systems and for use in cross-coupling reactions, facilitated by the reactive dioxolane protecting group.
• Chemical Biology: Useful as a molecular probe or tag in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-1,3-Dioxolane
CAS No.	1346597-53-2
Molecular Formula	C10H11FO4S
Molecular Weight	246.26 g/mol
Synonyms	2-(2-Fluoro-4-methanesulfonylphenyl)-1,3-dioxolane; 1,3-Dioxolane, 2-[2-fluoro-4-(methylsulfonyl)phenyl]-; 2-(2-Fluoro-4-(methylsulfonyl)phenyl)-1,3-dioxolane; 4-(1,3-Dioxolan-2-yl)-3-fluorophenyl methyl sulfone; 3-Fluoro-4-(1,3-dioxolan-2-yl)phenyl methyl sulfone
EINECS	Contact for details

Quality Control

Our production of 2-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-1,3-Dioxolane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the exacting requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.