Description

Benzenemethanol, 4-Chloro-2-Fluoro-α-Methyl-, (αs)- is a chiral fluorinated benzyl alcohol derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific stereochemistry and halogen substitution pattern are essential for biological activity. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating novel, high-performance molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and chlorine atoms enhance bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its aromatic and halogenated structure influences material properties.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control in related chemical processes.

Basic Information

Product Name	Benzenemethanol, 4-Chloro-2-Fluoro-α-Methyl-, (αs)-
CAS No.	1344929-92-5
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	(αS)-4-Chloro-2-fluoro-α-methylbenzenemethanol; (S)-1-(4-Chloro-2-fluorophenyl)ethanol; (S)-α-Methyl-4-chloro-2-fluorobenzyl alcohol; 4-Chloro-2-fluoro-α-methylbenzyl alcohol (S-enantiomer); (S)-4-Chloro-2-fluoro-α-methylbenzyl alcohol; Benzenemethanol, 4-chloro-2-fluoro-α-methyl-, (αS)-; (S)-1-(4-Chloro-2-fluorophenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 4-Chloro-2-Fluoro-α-Methyl-, (αs)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with exacting standards for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.