Description

4-Fluoro-2-(3,3,3-Trifluoropropoxy)Aniline is a specialized fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and a trifluoropropoxy substituent, makes it a high-value intermediate for creating compounds with enhanced metabolic stability and lipophilicity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profile.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Intermediate for synthesizing charge-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Fluorinated Polymer Research: Monomer or modifier for creating specialty polymers with unique surface properties and chemical resistance.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry and material science exploration, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Fluoro-2-(3,3,3-Trifluoropropoxy)Aniline
CAS No.	1344371-80-7
Molecular Formula	C9H9F4NO
Molecular Weight	223.17 g/mol
Synonyms	4-Fluoro-2-(3,3,3-trifluoropropoxy)benzenamine; 2-Amino-5-fluoro-1-(3,3,3-trifluoropropoxy)benzene; 1-Fluoro-4-(3,3,3-trifluoropropoxy)-2-aminobenzene; 4-Fluoro-2-(3,3,3-trifluoropropoxy)phenylamine; Benzenamine, 4-fluoro-2-(3,3,3-trifluoropropoxy)-; 1344371-80-7; 4-Fluoro-2-(3,3,3-trifluoropropoxy)aniline
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(3,3,3-Trifluoropropoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.