Description

n-[4-(Trifluoromethyl)Benzyl]Oxetan-3-Amine is a high-value, multifunctional chemical building block featuring a unique oxetane-amine scaffold. This compound is strategically important for its role in modern synthetic chemistry, particularly in the development of novel pharmaceuticals and advanced materials. It is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis due to its amine functionality and rigid oxetane ring.
• Material Science: Incorporated into polymers and advanced materials to modify thermal stability, solubility, and other physicochemical properties.
• Chemical Biology Probe Synthesis: Utilized in creating molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	n-[4-(Trifluoromethyl)Benzyl]Oxetan-3-Amine
CAS No.	1344265-97-9
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	3-[[[4-(Trifluoromethyl)phenyl]methyl]amino]oxetane; 1-[4-(Trifluoromethyl)benzyl]oxetan-3-amine; Oxetan-3-amine, N-[[4-(trifluoromethyl)phenyl]methyl]-; 4-(Trifluoromethyl)benzyl oxetan-3-ylamine; N-(4-(Trifluoromethyl)benzyl)oxetan-3-amine; (Oxetan-3-yl)[[4-(trifluoromethyl)phenyl]methyl]amine
EINECS	Contact for details

Quality Control

Our n-[4-(Trifluoromethyl)Benzyl]Oxetan-3-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.