Description

3-Thiazol-5-Yl-Alanine is a non-proteinogenic amino acid derivative featuring a thiazole heterocycle, a structure of significant interest in advanced organic synthesis and medicinal chemistry. This compound serves as a critical chiral building block for the development of novel pharmaceuticals and bioactive molecules, particularly in the design of enzyme inhibitors and peptide mimetics. It is essential for research and development chemists in the pharmaceutical, agrochemical, and biotechnology sectors seeking to incorporate unique heterocyclic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for targeted therapies.
• Peptidomimetics Design: Used to construct novel peptide analogs with enhanced metabolic stability and binding affinity by incorporating the thiazole moiety.
• Enzyme Inhibitor Synthesis: Serves as a core structure in creating potent inhibitors for various enzymatic targets.
• Agrochemical Research: Employed in the synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and protein functions.
• Ligand Development: Acts as a precursor for chelating ligands in catalysis and material science applications.

Basic Information

Product Name	3-Thiazol-5-Yl-Alanine
CAS No.	1343718-84-2
Molecular Formula	C₆H₈N₂O₂S
Molecular Weight	172.20 g/mol
Synonyms	5-(2-Amino-2-carboxyethyl)thiazole; (2S)-2-Amino-3-(1,3-thiazol-5-yl)propanoic acid; 3-(Thiazol-5-yl)-L-alanine; L-3-(5-Thiazolyl)alanine; 3-(1,3-Thiazol-5-yl)alanine; H-Thz(5)-OH; Thiazolylalanine
EINECS	Contact for details

Quality Control

Our 3-Thiazol-5-Yl-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) specifying identity, purity, and chiral excess is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.