Description

n-(4-Fluorobenzyl)Oxetan-3-Amine is a high-purity, specialized organic building block featuring a unique oxetane-amine scaffold with a fluorinated benzyl substituent. This compound is of significant value in modern synthetic chemistry for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, particularly for introducing the metabolically stable oxetane moiety and fluorine atom to modulate bioavailability and binding affinity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine and amine functional groups contribute to biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of monomers and polymers for advanced materials, including liquid crystals and high-performance resins.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tools to study biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific applications.

Basic Information

Product Name	n-(4-Fluorobenzyl)Oxetan-3-Amine
CAS No.	1342642-90-3
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-[(4-Fluorophenyl)methyl]aminooxetane; Oxetan-3-amine, N-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)oxetan-3-amine; 3-Aminooxetane, N-(4-fluorobenzyl)-; 4-Fluorobenzyl-oxetan-3-yl-amine; N-(4-Fluorobenzyl)oxetan-3-amine; (Oxetan-3-yl)(4-fluorobenzyl)amine; 1342642-90-3
EINECS	Contact for details

Quality Control

Our n-(4-Fluorobenzyl)Oxetan-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.