Description

4-Chloro-6-Pyrazol-1-Yl-Pyrimidin-5-Ylamine is a high-value pyrimidine-pyrazole heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its unique substitution pattern enables the creation of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Serves as a building block for creating tool compounds to study biological pathways and protein functions.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	4-Chloro-6-Pyrazol-1-Yl-Pyrimidin-5-Ylamine
CAS No.	1342392-11-3
Molecular Formula	C7H6ClN5
Molecular Weight	195.61 g/mol
Synonyms	5-Amino-4-chloro-6-(1H-pyrazol-1-yl)pyrimidine; 4-Chloro-6-(1H-pyrazol-1-yl)pyrimidin-5-amine; 4-Chloro-6-(pyrazol-1-yl)pyrimidin-5-amine; 4-Chloro-6-(1-pyrazolyl)-5-pyrimidinamine; 1342392-11-3; 5-Pyrimidinamine, 4-chloro-6-(1H-pyrazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Pyrazol-1-Yl-Pyrimidin-5-Ylamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) is supplied with every batch, detailing all relevant specifications to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.