Description

3-Fluoro-4-(Methoxymethyl)Aniline is a versatile fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a methoxymethyl group on the aniline ring, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other monomers used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polyimides, polyamides, and epoxy resins, improving thermal and chemical resistance.
• Dye & Pigment Manufacturing: Intermediate for synthesizing complex, high-performance fluorinated dyes and pigments with superior lightfastness and color properties.
• Cross-coupling Reactions: An ideal substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.

Basic Information

Product Name	3-Fluoro-4-(Methoxymethyl)Aniline
CAS No.	1341785-86-1
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	4-(Methoxymethyl)-3-fluoroaniline; 3-Fluoro-4-methoxymethylphenylamine; 3-Fluoro-4-(methoxymethyl)benzenamine; 1-Amino-3-fluoro-4-(methoxymethyl)benzene; Benzenamine, 3-fluoro-4-(methoxymethyl)-; 3-Fluoro-4-methoxymethyl aniline; 3-Fluoro-4-methoxymethylaniline; 3-Fluoro-4-(methoxymethyl)phenylamine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methoxymethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert atmosphere such as nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.