Description

2-[(1-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Piperidin-4-Yl)Oxy]Acetic Acid is a high-purity, specialized building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex biomolecules. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications in peptide synthesis, medicinal chemistry, and the creation of targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative or linker molecule.
• Fmoc-Protection Strategy: Serves as a reagent featuring the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, essential for orthogonal synthesis in peptide and organic chemistry.
• Medicinal Chemistry Research: Enables the construction of novel chemical entities for biological screening and structure-activity relationship (SAR) studies.
• Bioconjugation: Facilitates the attachment of pharmacophores or labels to biomolecules via its carboxylic acid and ether functionalities.
• Fine Chemical Synthesis: Employed in the production of high-value, complex organic molecules for various research and industrial applications.

Basic Information

Product Name	2-[(1-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Piperidin-4-Yl)Oxy]Acetic Acid
CAS No.	1341147-06-5
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	Fmoc-4-Hydroxypiperidine-O-acetic Acid; 1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-4-Hydroxypiperidine-O-acetic Acid; 4-[(Carboxymethoxy)-1-piperidinecarboxylic Acid 9H-Fluoren-9-Ylmethyl Ester; 1-Fmoc-4-Hydroxypiperidine-O-acetic Acid; 1-N-Fmoc-4-Hydroxypiperidine-O-acetic Acid; 4-(Carboxymethoxy)piperidine-1-carboxylic Acid 9-Fluorenylmethyl Ester; Piperidine-4-ol-O-acetic Acid, 1-Fmoc Derivative
EINECS	Contact for details

Quality Control

Our 2-[(1-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Piperidin-4-Yl)Oxy]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.