Description

4-Chloro-5-Ethyl-6-(Methylsulfanyl)-Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chloro, ethyl, and methylsulfanyl functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the research and production of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators requiring a substituted pyrimidine core.
• Material Science Research: Serves as a precursor for ligands and functional monomers in the synthesis of advanced polymers and coordination complexes.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to specific client molecular targets.
• Academic & Industrial R&D: Essential for methodological studies in heterocyclic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	4-Chloro-5-Ethyl-6-(Methylsulfanyl)-Pyrimidine
CAS No.	1340052-38-1
Molecular Formula	C7H9ClN2S
Molecular Weight	188.68 g/mol
Synonyms	4-Chloro-5-ethyl-6-(methylthio)pyrimidine; 5-Ethyl-4-chloro-6-methylsulfanylpyrimidine; 6-(Methylthio)-5-ethyl-4-chloropyrimidine; 4-Chloro-5-ethyl-6-methylmercaptopyrimidine; 4-Chloro-5-ethyl-6-(methylsulfanyl)pyrimidine; Pyrimidine, 4-chloro-5-ethyl-6-(methylthio)-; 1340052-38-1
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Ethyl-6-(Methylsulfanyl)-Pyrimidine undergoes rigorous analytical testing to ensure it meets the high-purity standards required for synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.