Description

1-(Pyrimidin-4-Yl)Azetidine-3-Carboxylic Acid is a high-value heterocyclic building block featuring a fused azetidine and pyrimidine scaffold. This compound is of significant interest for its role as a key intermediate in modern pharmaceutical research and development, particularly in the synthesis of novel small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to develop new active ingredients with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and target validation.
• Agrochemical Development: Potential intermediate in the research of new fungicides or herbicides with novel modes of action.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	1-(Pyrimidin-4-Yl)Azetidine-3-Carboxylic Acid
CAS No.	1339670-12-0
Molecular Formula	C8H9N3O2
Molecular Weight	179.18 g/mol
Synonyms	Azetidine-3-carboxylic acid, 1-(4-pyrimidinyl)-; 1-(Pyrimidin-4-yl)azetidine-3-carboxylic acid; 3-Carboxy-1-(pyrimidin-4-yl)azetidine; 1-(4-Pyrimidinyl)azetidine-3-carboxylic acid; Azetidine-3-carboxylic acid, 1-(4-pyrimidinyl)- (9CI); 1339670-12-0
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-4-Yl)Azetidine-3-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.