Description

Phenol, 4-(Cyclohexylideneamino)-3-Fluoro- is a specialized fluorinated phenol derivative featuring a cyclohexylideneamino substituent. This unique molecular architecture makes it a valuable high-purity intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active ingredients. The compound is supplied with full traceability under CAS number 1338722-54-5.

Application

This fluorinated intermediate is designed for sophisticated chemical synthesis, primarily serving the following applications:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom and phenolic structure can contribute to biological activity and environmental persistence profiles.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, or specialty coatings with specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized in creating labeled compounds or affinity probes for studying enzyme mechanisms or protein-ligand interactions due to its reactive phenolic and imine functionalities.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) for constructing complex biaryl or aniline structures.

Basic Information

Product Name	Phenol, 4-(Cyclohexylideneamino)-3-Fluoro-
CAS No.	1338722-54-5
Molecular Formula	C12H14FNO
Molecular Weight	207.25 g/mol
Synonyms	4-[(Cyclohexylidene)amino]-3-fluorophenol; 3-Fluoro-4-(cyclohexylideneamino)phenol; 4-(Cyclohexylidenamino)-3-fluorophenol; N-Cyclohexylidene-3-fluoro-4-aminophenol; 3-Fluoro-4-[(cyclohexylidene)amino]phenol; 4-(Cyclohexylideneimino)-3-fluorophenol
EINECS	Contact for details

Quality Control

We supply Phenol, 4-(Cyclohexylideneamino)-3-Fluoro- as a high-purity research chemical. Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to a strict quality management system to guarantee batch-to-batch consistency and reliability for your critical research and development projects. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.