Description

2-(Chloromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine is a high-value heterocyclic building block featuring a reactive chloromethyl group fused to a triazolopyrimidine core. This compound is critical for medicinal chemistry and agrochemical research, serving as a versatile intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds and molecular probes for target identification and validation studies.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and functional materials with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-(Chloromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine
CAS No.	1338495-29-6
Molecular Formula	C7H5ClN4
Molecular Weight	180.59 g/mol
Synonyms	2-(Chloromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine; 2-(Chloromethyl)-1,2,4-triazolo[1,5-a]pyrimidine; 2-(Chloromethyl)-1,2,4-triazolopyrimidine; 2-(Chloromethyl)-1,2,4-triazolo[1,5-a]pyrimidine; 1338495-29-6; Triazolopyrimidine chloromethyl derivative
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.