Description

6-(Dimethylamino)-5-Fluoropyrimidin-2(1H)-One CAS NO 1338494-87-3 is a high-value fluorinated pyrimidinone derivative, a key advanced intermediate in modern synthetic chemistry. Its molecular structure, featuring both a dimethylamino and a fluorine substituent, makes it a versatile building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its fluorinated heterocyclic core.
• Organic Synthesis Building Block: A valuable reagent for constructing complex pyrimidine-based scaffolds in academic and industrial R&D laboratories.
• Material Science Research: Investigated for the creation of novel organic electronic materials or specialty polymers.
• Bioconjugate Chemistry: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.

Basic Information

Product Name	6-(Dimethylamino)-5-Fluoropyrimidin-2(1H)-One
CAS No.	1338494-87-3
Molecular Formula	C6H8FN3O
Molecular Weight	157.15 g/mol
Synonyms	5-Fluoro-6-(dimethylamino)pyrimidin-2(1H)-one; 5-Fluoro-6-(dimethylamino)-2-hydroxypyrimidine; 6-(Dimethylamino)-5-fluoro-1H-pyrimidin-2-one; 6-(Dimethylamino)-5-fluoropyrimidin-2-ol; 5-Fluoro-6-(N,N-dimethylamino)uracil; 1338494-87-3; 6-Dimethylamino-5-fluoropyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-(Dimethylamino)-5-Fluoropyrimidin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), please contact our technical team to discuss your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.