Description

(4-Bromo-2-Chloro-5-Fluoro-Phenyl)-Methanol is a high-purity fluorinated aromatic alcohol building block of significant importance in advanced organic synthesis. Its value lies in its versatile halogenated structure, which serves as a critical intermediate for constructing complex molecules in regulated industries. This compound is primarily needed by pharmaceutical R&D teams and agrochemical manufacturers for the development of new active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its halogen pattern contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), enhancing performance and stability.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to build complex biaryl systems.
• Functional Polymer Monomer: Can be incorporated as a side-chain modifier or end-capper in specialty polymers to impart specific chemical resistance or optical properties.
• Chemical Research & Development: Employed in academic and industrial labs as a versatile building block for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	(4-Bromo-2-Chloro-5-Fluoro-Phenyl)-Methanol
CAS No.	1338254-21-9
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	4-Bromo-2-chloro-5-fluorobenzyl alcohol; (4-Bromo-2-chloro-5-fluorophenyl)methanol; 1-(Bromochlorofluorophenyl)methanol; 2-Chloro-4-bromo-5-fluorobenzyl alcohol; α-Hydroxymethyl-4-bromo-2-chloro-5-fluorobenzene; Benzenemethanol, 4-bromo-2-chloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Chloro-5-Fluoro-Phenyl)-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.