Description

5-Chloromethyl-Pyrimidine Hydrochloride is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its primary importance lies in its reactive chloromethyl group, which facilitates efficient alkylation and functionalization reactions to create complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Useful for modifying biomolecules or creating tool compounds for target identification and validation in drug discovery.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Chloromethyl-Pyrimidine Hydrochloride
CAS No.	1337879-54-5
Molecular Formula	C5H6Cl2N2
Molecular Weight	165.02 g/mol
Synonyms	Pyrimidine, 5-(chloromethyl)-, hydrochloride (1:1); 5-(Chloromethyl)pyrimidine hydrochloride; 5-(Chloromethyl)pyrimidine HCl; 5-Chloromethylpyrimidine HCl; 5-Pyrimidinemethanol, 1-chloro-, hydrochloride; 5-(Chloromethyl)pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chloromethyl-Pyrimidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.