Description

5-Bromo-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical and agrochemical research. Its value lies in its functionalized pyrrolopyrimidine core, which is a privileged scaffold for designing potent kinase inhibitors and other biologically active molecules. This intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to develop novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of targeted kinase inhibitors, particularly in oncology and inflammatory disease research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Biochemical Research: Serves as a precursor for labeled compounds or probes used in biochemical assays and target validation.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides or fungicides with specific modes of action.
• Process Chemistry: Utilized in route scouting and scale-up development for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.

Basic Information

Product Name	5-Bromo-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	1337532-51-0
Molecular Formula	C7H7BrN4
Molecular Weight	227.06 g/mol
Synonyms	4-Amino-5-bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine; 5-Bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-bromo-7-methyl-; 5-Bromo-7-methyl-pyrrolo[2,3-d]pyrimidin-4-ylamine; 1337532-51-0; 5-Br-7-Me-7H-pyrrolo[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.