Description

2-Chloro-4-Methoxy-L-Phenylalanine is a non-natural, chiral amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing specific structural motifs and functional groups into target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for peptide-based therapeutics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active compounds for crop protection products.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships or to create peptide mimetics with enhanced properties.
• Chemical Biology Research: Serves as a probe or a modified amino acid residue to investigate protein function and interactions.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral centers.
• Ligand and Catalyst Development: Used in the design and synthesis of novel chiral ligands for metal-catalyzed transformations.

Basic Information

Product Name	2-Chloro-4-Methoxy-L-Phenylalanine
CAS No.	1335546-83-2
Molecular Formula	C10H12ClNO3
Molecular Weight	229.66 g/mol
Synonyms	(2S)-2-Amino-3-(2-chloro-4-methoxyphenyl)propanoic acid; L-2-Chloro-4-methoxyphenylalanine; (S)-2-Amino-3-(2-chloro-4-methoxyphenyl)propionic acid; 2-Chloro-4-methoxy-L-phenylalanine; 2-Cl-4-MeO-L-Phe; 2-Chloro-4-methoxy-DL-phenylalanine (related racemic mixture); 2-Chloro-4-methoxyphenylalanine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxy-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.