Description

Ds-1040 (Tosylate) is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate, identified by CAS NO 1335138-89-0. This compound is a critical building block in the synthesis of advanced pharmaceutical active ingredients, offering precise chemical functionality for complex molecular construction. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of antiviral therapeutics and other fine chemical synthesis projects.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiviral drug discovery and development.
• Antiviral Research: Serves as a crucial scaffold in medicinal chemistry for designing and testing novel compounds targeting viral replication mechanisms.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce specific functional groups in complex molecule construction.
• Biochemical Research: Employed in biochemical assays and studies to understand enzyme inhibition and mechanism of action.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the scale-up and cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional laboratories for exploratory chemistry and drug development projects.

Basic Information

Product Name	Ds-1040 (Tosylate)
CAS No.	1335138-89-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DS-1040 Tosylate; DS1040 Tosylate; Ds-1040 Tosylate Salt; 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile Monotosylate; BMS-955176 Tosylate; GSK-2838232 Tosylate; (Alternative names based on parent compound structure)
EINECS	Contact for details

Quality Control

Our Ds-1040 (Tosylate) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.