Description

2-Bromo [1,2,4]Triazolo[1,5-A]Pyrimidine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and reactive intermediate, enabling the construction of complex molecular architectures through cross-coupling and nucleophilic substitution reactions. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form new carbon-carbon and carbon-heteroatom bonds.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical space.

Basic Information

Product Name	2-Bromo [1,2,4]Triazolo[1,5-A]Pyrimidine
CAS No.	1335054-80-2
Molecular Formula	C5H2BrN5
Molecular Weight	212.00 g/mol
Synonyms	2-Bromo[1,2,4]triazolo[1,5-a]pyrimidine; 2-Bromo-1,2,4-triazolo[1,5-a]pyrimidine; 2-Bromotriazolopyrimidine; 2-Bromo-[1,2,4]triazolo[1,5-a]pyrimidine; 1335054-80-2; BTP-Br; 2-Br-TP
EINECS	Contact for details

Quality Control

Our 2-Bromo [1,2,4]Triazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.