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n-((5-(4-Chloroquinazolin-6-Yl)Furan-2-Yl)Methyl)-2-(Methylsulfonyl)Ethanamine CAS NO 1334953-75-1


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CAS No.:1334953-75-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-((5-(4-Chloroquinazolin-6-Yl)Furan-2-Yl)Methyl)-2-(Methylsulfonyl)Ethanamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazoline-furan hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel small-molecule drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology and targeted therapies.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates, particularly in oncology.
  • Biochemical Tool Compound: Serves as a reference standard or a probe in biochemical and pharmacological assays to study specific biological pathways.
  • Contract Research & Development (CRO): Supplied to CROs and CDMOs for custom synthesis projects and pre-clinical development.
  • Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name n-((5-(4-Chloroquinazolin-6-Yl)Furan-2-Yl)Methyl)-2-(Methylsulfonyl)Ethanamine
CAS No. 1334953-75-1
Molecular Formula C₁₆H₁₄ClN₃O₃S
Molecular Weight 363.82 g/mol
Synonyms 2-(Methylsulfonyl)-N-[[5-(4-chloro-6-quinazolinyl)-2-furanyl]methyl]ethanamine; N-((5-(4-Chloroquinazolin-6-yl)furan-2-yl)methyl)-2-(methylsulfonyl)ethanamine; 1334953-75-1; Ethanamine, 2-(methylsulfonyl)-N-[[5-(4-chloro-6-quinazolinyl)-2-furanyl]methyl]-; (5-(4-Chloroquinazolin-6-yl)furan-2-yl)methanamine derivative
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Quality Control

Every batch of n-((5-(4-Chloroquinazolin-6-Yl)Furan-2-Yl)Methyl)-2-(Methylsulfonyl)Ethanamine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications suitable for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Any individual impurity ≤ 0.5%
Total Impurities ≤ 2.0%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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