Description

6-(5-((2-(Methylsulfonyl)Ethylamino)Methyl)Furan-2-Yl)Quinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory treatments. The material is supplied with full analytical documentation to support critical drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent and selective kinase inhibitors for targeted cancer therapies.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization of quinazolinone-based drug candidates.
• Biochemical Tool Compound: Serves as a reference standard or a probe molecule in enzymatic assays and cellular pathway analysis within academic and industrial R&D labs.
• API Synthesis: Employed in the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) with specific kinase modulation activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions as required.

Basic Information

Product Name	6-(5-((2-(Methylsulfonyl)Ethylamino)Methyl)Furan-2-Yl)Quinazolin-4(3H)-One
CAS No.	1334953-74-0
Molecular Formula	C₁₇H₁₉N₃O₄S
Molecular Weight	361.42 g/mol
Synonyms	4(3H)-Quinazolinone, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-; 6-(5-((2-(Methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-ol; 1334953-74-0; Quinazolin-4(3H)-one, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-; 6-(5-(((2-(Methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Every batch of 6-(5-((2-(Methylsulfonyl)Ethylamino)Methyl)Furan-2-Yl)Quinazolin-4(3H)-One is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.