Description

1-(2,4-Difluorophenyl)Pyrrolidine is a high-value fluorinated pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluorophenyl moiety, is engineered to modulate the physicochemical and metabolic properties of target molecules, making it indispensable for research and development. This intermediate is primarily sought after by pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its aromatic and heterocyclic components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Pyrrolidine
CAS No.	1334499-91-0
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	1-(2,4-Difluorophenyl)pyrrolidine; Pyrrolidine, 1-(2,4-difluorophenyl)-; 2,4-Difluoro-1-(pyrrolidin-1-yl)benzene; N-(2,4-Difluorophenyl)pyrrolidine; 1-(2,4-Difluorophenyl)-1-azacyclopentane
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.