Description

5-Bromo-4-Fluoroanthranilonitrile, also known as 4-Bromo-2-Cyano-5-Fluoroaniline, is a high-purity, multi-functional halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, fluorine, and nitrile functional groups, makes it an indispensable intermediate for constructing complex heterocyclic systems and fine-tuning molecular properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast dyes and functional pigments.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for biochemical probes.

Basic Information

Item	Information
Product Name	5-Bromo-4-Fluoroanthranilonitrile, 4-Bromo-2-Cyano-5-Fluoroaniline
CAS No.	1334331-01-9
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	4-Bromo-2-cyano-5-fluoroaniline; 5-Bromo-4-fluoro-2-aminobenzonitrile; 2-Amino-4-bromo-5-fluorobenzonitrile; 4-Bromo-5-fluoroanthranilonitrile; 5-Fluoro-4-bromoanthranilonitrile; 2-Cyano-4-bromo-5-fluoroaniline; 4-Bromo-5-fluoro-2-aminobenzonitrile; 2-Amino-5-fluoro-4-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoroanthranilonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.