Description

3-Fluoro-4-(1-Methyl-5,6-Dihydro-1H-[1,2,4]Triazin-4-Yl)-Phenylamine (Wxg00213) is a high-purity, advanced pharmaceutical intermediate featuring a unique triazine-phenylamine scaffold. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel small-molecule drug candidates. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on oncology, CNS disorders, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its fluorinated aromatic and heterocyclic structure.
• Kinase Inhibitor Development: Serves as a core scaffold in the design and development of potential kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in custom, multi-step synthetic routes for clients.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	3-Fluoro-4-(1-Methyl-5,6-Dihydro-1H-[1,2,4]Triazin-4-Yl)-Phenylamine (Wxg00213)
CAS No.	1334167-69-9
Molecular Formula	C10H12FN5
Molecular Weight	221.24 g/mol
Synonyms	4-(4-Amino-2-fluorophenyl)-1-methyl-5,6-dihydro-1H-[1,2,4]triazine; 3-Fluoro-4-(1-methyl-5,6-dihydro-1H-1,2,4-triazin-4-yl)aniline; WXG00213; 1-Methyl-4-(4-amino-2-fluorophenyl)-5,6-dihydro-1H-1,2,4-triazine; 1334167-69-9; 4-(4-Amino-2-fluorophenyl)-1-methyl-4,5-dihydro-1H-1,2,4-triazine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(1-Methyl-5,6-Dihydro-1H-[1,2,4]Triazin-4-Yl)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maximize stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.